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The cytotoxic effects of ZON are, in part, thought to be correlated with its apoptotic potential by activation of mitochondrial cytochrome c , ROS production, induction of caspase-3/8, and ER stress in human leukemia cells (Table 2) (72)

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[DOI] [PubMed] [Google Scholar] 123.Rafiee Z, Nejatian M, Daeihamed M, Jafari SM